Marijuana and Medicine

[Tim]

To second or third this, cannabis hyperemesis is real. As a hospitalist just trust me
im in CO so I see a lot of this

The only known effective treatment for CHS is to stop using cannabis.^{[1]
Good luck with that.}

[Bellescamp]

To second or third this, cannabis hyperemesis is real. As a hospitalist just trust me

They always deny it, one trick is ask them what makes it better. For some reason long hot showers seem to mitigate the symptoms. They all are very clean….

I don’t know the science behind the “amotivational syndrome” but anecdotally seems to be real

and lots of data on deleterious effects of chronic use on developing teenage minds

im in CO so I see a lot of this

[Huggy]

i dont think many people are truthfully arguing for medical use, and when alcohol was illegal the same "medical" arguments were around, probably not related.

This.

The whole medicinal marijuana business is simply a roundabout way of accessing high quality buds legally since our government continues to drag their feet on nationwide recreational marijuana legislation. Now if recreational marijuana was legalized, I'd imagine there wouldn't be much conversation at all on the medicinal benefits of the substance. You wouldn't need to justify why you get high, for the same reason that nobody needs to justify getting buzzed/drunk on a weekend.

[Zaphod]

Maybe, sure.

But unless you encounter someone with methanol poisoning who just so happens to be in a bar and/or nowhere near a hospital, then nobody is suggesting alcohol as medical treatment.

The comparison of marijuana to alcohol is completely irrelevant, medically.

i dont think many people are truthfully arguing for medical use, and when alcohol was illegal the same "medical" arguments were around, probably not related.

[xraygoggles]

even if you did, no one would want them haha

Yep.

[Sampter]

But unless you encounter someone with methanol poisoning who just so happens to be in a bar and/or nowhere near a hospital, then nobody is suggesting alcohol as medical treatment.

.

John Wick would disagree with you.

[bovie]

weed is better than alcohol in almost every way.

Hangover :Better (I would prefer my surgeon to have smoked the night before than drank)
Chronic use is safer
not teratogenic
more fun?(maybe not in all situations)
less violence
food tastes better
movies are funnier
great for GI issues


What are the pros of alcohol besides decreasing my inhibitions?
80% of my bad decisions in my life probably revolve around alcohol

I guess eating more is def a downside of marijuana but who didnt late night eat after a night of drinking?

All the negatives you guys say of marijuana, alc is way worse. You think drinking alcohol makes me more motivated?

Clearly im not biased

Maybe, sure.

But unless you encounter someone with methanol poisoning who just so happens to be in a bar and/or nowhere near a hospital, then nobody is suggesting alcohol as medical treatment.

The comparison of marijuana to alcohol is completely irrelevant, medically.

[Bdoc]

weed is better than alcohol in almost every way.

Hangover :Better (I would prefer my surgeon to have smoked the night before than drank)
Chronic use is safer
not teratogenic
more fun?(maybe not in all situations)
less violence
food tastes better
movies are funnier
great for GI issues


What are the pros of alcohol besides decreasing my inhibitions?
80% of my bad decisions in my life probably revolve around alcohol

I guess eating more is def a downside of marijuana but who didnt late night eat after a night of drinking?

All the negatives you guys say of marijuana, alc is way worse. You think drinking alcohol makes me more motivated?

Clearly im not biased

[Zaphod]

Part of my PhD work focused on trying to synthesize chemicals that selectively activated CB2 receptors compared to CB1 (i.e. compounds that had similar positive effects without the high). Failed to find a useful compound, unfortunately…

even if you did, no one would want them haha

[Zaphod]

To most people, medicine is about doing something. A lot of stuff that gets prescribed in medicine doesn’t do a whole lot or doesn’t really have much evidence. If people watched what they ate, loss some weight, and got more active, I think they’d find that they would magically feel better in multiple ways.

The 5’7” 325lb dude with back pain doesn’t want to hear, “hey, I bet if you lost some weight and did some core strengthening then your back would probably start feeling better and wouldn’t hate you all the time”. He wants his pain to magically disappear. He inevitably gets multiple medicines that have zero to minimal benefit and time does it’s thing until his back decides it’s had enough again a few weeks/months later and we start the cycle over.

yeah, my view is its recreational (for the great majority that talk medical even, though could be something, ppl want recreational and others arent even a rounding error), alcohol had touted "medicinal" benefits as well prior to legalization, its how we approach it.

[CordMcNally]

This is like the 4th mention of CBD, it has been studied a decent amount. CBD does nothing, not a dang thing. Its legal even in states like mine where there is no rec or medical use.

Im sure weed works decently for low key ailments/anxiety and would be a great substitute for opioids/alcohol, but like anything could be abused, safety profile is wider than alcohol though. Nothing is good to excess.

To most people, medicine is about doing something. A lot of stuff that gets prescribed in medicine doesn’t do a whole lot or doesn’t really have much evidence. If people watched what they ate, loss some weight, and got more active, I think they’d find that they would magically feel better in multiple ways.

The 5’7” 325lb dude with back pain doesn’t want to hear, “hey, I bet if you lost some weight and did some core strengthening then your back would probably start feeling better and wouldn’t hate you all the time”. He wants his pain to magically disappear. He inevitably gets multiple medicines that have zero to minimal benefit and time does it’s thing until his back decides it’s had enough again a few weeks/months later and we start the cycle over.

[bovie]

this is absurd. no one should practice impaired. if my surgeon smoked a joint the night before why would I care?

Clearly you've never woken up still high

[triad]

So would you accept light marijuana use in a physician or surgeon who is treating you ? Just like, maybe a little before the or to calm the nerves?

this is absurd. no one should practice impaired. if my surgeon smoked a joint the night before why would I care?

[childay]

CBD has efficacy for 3 specific seizure disorders. I believe I heard about it on radiolab first. The types of seizure disorders are mentioned in this article-

https://www.hopkinsmedicine.org/news/newsroom/news-releases/cbd-products-may-help-people-with-epilepsy-better-tolerate-anti-seizure-medications

Interesting. The article you link appears to be not placebo controlled trial.
But FDA approval was based on several that were

https://www.fda.gov/drugs/drug-approvals-and-databases/drug-trials-snapshots-epidiolex

Who knows what you're getting from a "CBD" product or most supplements. Anecdotally, today my patient says "I never believed in CBD at all until I tried it" for pain. Placebo effect? Thats why we do RCTs..

[Brains428]

This is like the 4th mention of CBD, it has been studied a decent amount. CBD does nothing, not a dang thing. Its legal even in states like mine where there is no rec or medical use.

Im sure weed works decently for low key ailments/anxiety and would be a great substitute for opioids/alcohol, but like anything could be abused, safety profile is wider than alcohol though. Nothing is good to excess.

CBD has efficacy for 3 specific seizure disorders. I believe I heard about it on radiolab first. The types of seizure disorders are mentioned in this article-

https://www.hopkinsmedicine.org/news/newsroom/news-releases/cbd-products-may-help-people-with-epilepsy-better-tolerate-anti-seizure-medications