Marijuana and Medicine

[F0017S0]

Part of my PhD work focused on trying to synthesize chemicals that selectively activated CB2 receptors compared to CB1 (i.e. compounds that had similar positive effects without the high). Failed to find a useful compound, unfortunately…

[Zaphod]

Honestly, Id rather a patient use a quality controlled CBD product than chronic opioids or even long term NSAIDs.

This is like the 4th mention of CBD, it has been studied a decent amount. CBD does nothing, not a dang thing. Its legal even in states like mine where there is no rec or medical use.

Im sure weed works decently for low key ailments/anxiety and would be a great substitute for opioids/alcohol, but like anything could be abused, safety profile is wider than alcohol though. Nothing is good to excess.

[The White Coat Investor]

What is this?

Has there ever been studies showing that you can experience overdose or withdrawal from weed? It's not like heroin or cocaine, where certain neural pathways are activated and there are adverse physiological effects over the long term.

No man, it's the cyclic vomiting syndrome you have to watch out for. And good luck ever convincing a patient it's caused by the weed.

I imagine most GI docs hate it for this reason. I know emergency docs do. If you're smoking enough of it to treat chronic pain, you're smoking enough to get CVS. And if you do, best to just admit it's the weed and fine something else for your pain. Even opiates must be better than being in the ER twice a month hoping haldol will help you stop vomiting.

[childay]

Cannabinoid hyperemesis syndrome is supposedly rare but it doesn't seem very rare in the ED. Maybe the most frustrating part is that the solution is simple yet a majority of people refuse to quit smoking weed every day.

Agreed every time I've seen it they absolutely do not believe me even if I find something online or whatever.

Evidence for medical use is virtually nonexistant. Medical cannabis is a sham. I would rather they legalize it than have the farce of medical cards.

[Tangler]

The daily habit developed in high school and early college seems to have ruined motivation for two nephews and a lot of their friends. Recreational ABUSE is catastrophic on families. Basically the impact on motivation. Just observations, no data.

“Alcohol, tobacco, opioids, cocaine/meth.” I don’t think recreational ABUSE of these means weed should be encouraged.

The last thing i personally need is less motivation and more appetite.

America?

Does the typical American need more appetite?

Less motivation?

I don’t think so but I am not going to win that war nor fight it ( told you i lack motivation)

[Otolith]

Live in recreational state. Had a few patients that used edibles post op tonsillectomy and had anecdotal pain relief. I don't endorse it but I let my post op patients use it.

My take is there is something there but not a cure all.

Think about how many conditions are either caused by or made worse due to hyperfixation/anxiety/stress. If THC/CBD helps you forget about your issue and relax your muscles I can see that being helpful for a lot of people. Not perfect but helpful

To answer original question: There are literally (maybe even shady)people who have a full time job to provide medical cards. Send patients to a medical dispensary and let them self dose/titrate. You know they are going to come back telling you what dose/tincture works for "my body" anyways...

[8arclay]

So would you accept light marijuana use in a physician or surgeon who is treating you ? Just like, maybe a little before the or to calm the nerves?

To be clear, my comment was towards CBD-only/minimal THC products.

[Random1]

So would you accept light marijuana use in a physician or surgeon who is treating you ? Just like, maybe a little before the or to calm the nerves?

[8arclay]

Honestly, Id rather a patient use a quality controlled CBD product than chronic opioids or even long term NSAIDs.

[bovie]

correlation or causation.

i know plenty of people with no motivation who barely drink.

i know plenty of MJ users who are hyper productive.

So what you’re saying, is that there are exceptions to every rule or trend. Of course.

On the whole, I find it hard to argue that heavy marijuana use or abuse does not contribute to decreased motivation—and not uncommonly to a significant degree.

[Tim]

correlation or causation.

i know plenty of people with no motivation who barely drink.

i know plenty of MJ users who are hyper productive.

ABUSER was intentionally capitalized. Each of the items impact differently. Tobacco doesn’t “impair”.
I doubt you would take action if an ED doc smoked a cigarette on the way to work vs getting high and trying to work or was loaded. Recreation an abuse are two different things.
Alcohol or MJ abuse can both cause serious problems if ABUSED.
Tobacco- I dealt with a nephew Saturday. He was smoking on the porch at an engagement party for his sister. I took him down 25 floors to the street where he could smoke. Yes, he is one that had an MJ problem. I don’t know if he kicked the daily MJ problem. I really don’t care the cause. He has issues, but not my problem. I handled the tobacco issue. Not his parents, but they complain and paying his student loans. He could do better, I doubt he would be a high achiever. Getting high daily certainly wouldn’t help. I hope he isn’t drunk daily. He has a kid and a partner living with parents. Sad case. I hope he gets productive.

[MPMD]

The daily habit developed in high school and early college seems to have ruined motivation for two nephews and a lot of their friends. Recreational ABUSE is catastrophic on families. Basically the impact on motivation. Just observations, no data.

“Alcohol, tobacco, opioids, cocaine/meth.” I don’t think recreational ABUSE of these means weed should be encouraged.

correlation or causation.

i know plenty of people with no motivation who barely drink.

i know plenty of MJ users who are hyper productive.

[Tim]

endorse

i don't really know anyone who feels that strongly about weed anymore, even super conservative people i know don't really seem to care.

The daily habit developed in high school and early college seems to have ruined motivation for two nephews and a lot of their friends. Recreational ABUSE is catastrophic on families. Basically the impact on motivation. Just observations, no data.

“Alcohol, tobacco, opioids, cocaine/meth.” I don’t think recreational ABUSE of these means weed should be encouraged.

[bovie]

That's because pot IS much stronger than it was in the past. It has like double the amount of THC on average (ish. I can't remember exact numbers).

Try 5-10x.

[GIMD]

I've seen marijuana-induced psychosis and plenty of cases of cannabis hyperemesis syndrome so it's not a benign drug. Currently, I don't feel comfortable recommending or prescribing marijuana since there is a lack of data on its efficacy but I am willing to learn. I think it's only officially approved for post chemotherapy nausea/vomiting and certain hereditary seizure disorders. I think categorizing marijuana as Schedule I, the same category as heroin, is ridiculous. It makes research virtually impossible so what ends up happening is legalization at the state level with no regulation and no data. The stuff that gets sold at dispensaries probably has way too much THC/CBD than is needed for any kind of medical benefit. I guess we will just have to rely on our neighbor to tell us if/how to use marijuana in medicine.