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Originally posted by CordMcNally View Post
Huh?
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Originally posted by burritos View Post
I have the "eating disorder" where I when I work I only eat and drink(2-4 cups of water/tea/etoh) during dinner, nothing for the rest of my day. Been doing this for almost 4 years. 3-4/wk. While I work I still urinate throughout the day. It's not voluminous, maybe 3-400cc. Mouth is never dry, I go outside to spit throughout the day. The urine is a light yellow. Never dark. I can always see the toilet bowl stains through the urine, even after housekeeping has cleaned it. When I first started doing this, my UA had ketones, but those are gone as of 2 years ago. I think I have renal resorption of ketones as to not waste energy.
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Originally posted by burritos View Post
It takes energy and Na for the kidney to clear free water, but if that's what you have to do to not have stones, then you gotta do what you gotta do. BTW, my understanding is that nephrons require more energy than any other cell even beyond neurons and hepatocytes. That's why CKD is prevalent when your bioenergetics becomes dysfuctional(ie. IR and DM). If you kidney energy demands aren't met, well it starts to fail.
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Originally posted by K82 View Post
That's interesting. I always thought that neurons were the most energy hungry.
It's a pain to drink that much water daily, I definitely wouldn't do it if I didn't have to.
the human kidneys constitute only 0.5%of body mass, they consume 10%of the oxygen used in cellular respiration
While the brain represents just 2% of a person's total body weight, it accounts for 20% of the body's energy use
https://www.ncbi.nlm.nih.gov/pmc/art...0and%20tissues.
Ranking of energy by density is 1. Heart. 2. Kidney. 3. Brain. 4. Liver
Ranking of total energy usage by organ 1. Liver. 2. Brain. 3. Heart 4. Kidney.
I think most people wouldn't guess that the by organ, liver uses the most energy.
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Originally posted by burritos View Post
It takes energy and Na for the kidney to clear free water, but if that's what you have to do to not have stones, then you gotta do what you gotta do. BTW, my understanding is that nephrons require more energy than any other cell even beyond neurons and hepatocytes. That's why CKD is prevalent when your bioenergetics becomes dysfuctional(ie. IR and DM). If you kidney energy demands aren't met, well it starts to fail.
It's a pain to drink that much water daily, I definitely wouldn't do it if I didn't have to.
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Originally posted by K82 View Post
I'm not a urologist but I understand that the standard recommendation for stone former's is to PRODUCE 3 L of urine a day, not just drink 3L. Any urologists on the forum recommend anything different?
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Originally posted by Lordosis View Post
My goal it to get the urine clear or close to it by mid day. I do not have any data to support this but it is just what I shoot for.
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Originally posted by Zaphod View Post
How does extra water factor into that, you make most of your water via food, and soda and other things have water as well. If urine is relatively dilute already, makes no sense.
In ever discussing these topics, we shouldnt be focusing general takes on outliers.
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Originally posted by K82 View Post
Experiencing a kidney stone may change your opinion....
In ever discussing these topics, we shouldnt be focusing general takes on outliers.
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Originally posted by Kamban View Post
Unless you do a randomized trial with matched numbers for having a predilection for kidney stones and one group drinks normal amounts of water during the day and other takes excess to flush the kidneys and find out if the control group has statically increased chances of having a stone, all this is conjecture and wishful thinking.
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Can how yellow the urine is be a gross proxy as to how concentrated the urine is?
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Originally posted by K82 View Post
Yes, my understanding is that it keeps the tubules flushed out and prevents stone formation. But the flip side is that a lack of enough water allows stone formation.
Last edited by Kamban; 09-29-2022, 09:42 AM.
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I try to force fluid consumption bc I am hypertensive by design (thanks mom and dad). My personal BP goal is below 120 systolic based on results of the SPRINT-MIND paper. So I’m on 2 agent therapy. If I get volume down at all, I get severe orthostatic hypotension. I also drink about 12 cups of coffee per day and forget to drink or eat for hours on end while working, so I have to make a conscious effort to drink.
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