Medical Discussion of Coronavirus

[Tim]

Tim ucsd reached out to padres baseball since we have existing ties covering their team and they jumped at this.. Petco park events team and our engineers stood this up in 72hours.

Events team traffic control Ucsd it team deployed scheduling system
Ucsd medical command and control... registration to vaccine administration.
county supplied vaccines
County emt and private medical fill in on vaccine teams and will redeploy to new sites
Current flow capacity. 5k per day.

Yeah can replicate on scale if enough parking space.

Places like football stadium and disneyland should be able to do 15-20k easy. The lynchpin remains sufficient skilled vaccinators.

https://www.google.com/amp/s/www.click2houston.com/news/local/2021/01/19/turner-explains-what-caused-some-to-be-turned-away-from-saturdays-vaccine-megasite-at-minute-maid-park/%3foutputType=amp

Some do it right and some do it wrong. Please suggest the Padres touch base with the Astros, SanDiego County with Harris County, your medical wizards with the appropriate medical wizards. Three key players in each model is critical. Standing in line for a wrist bands is asking for failure. I am serious. MinuteMaid Park has zero onsite parking. That is a huge negative.
•Much better alternatives. NRG(Texans), UofH and Rice stadiums, shopping centers etc. Drive thru is a premium, even rotating with HS stadiums/parking lots. Scale it. The process works.
I trust your comment about “skilled vaccinators”.
That can be worked as needed.
Supercomputer and distributed processing both have advantages. Processing speed is needed.

[Bmac]

Here in Washington State, Governor Inslee is trying to enlist corporate support and assistance from Starbucks, Microsoft and Costco, among others. Hopefully his goal of 40,000 + vaccinations a day can be achieved.

https://abcnews.go.com/Business/washington-state-taps-starbucks-microsoft-costco-aid-vaccine/story?id=75340943

[Lithium]

Fortunately I had no issues with my second dose. Thanks to the forum for helping me overcome being a pansy.

Looking forward to Maui in two months.

[Tim]

Fortunately I had no issues with my second dose. Thanks to the forum for helping me overcome being a pansy.

Looking forward to Maui in two months.

Might want to be aware of potential interstate travel restrictions. Vaccinated or not, the mood at the top has shifted.

[StarTrekDoc]

Also have Maui on tap: 3/14 - Hopefully the club will be open to dining. We've pushed our Hawaii trip 3 times in 2020 already.

[Lithium]

Also have Maui on tap: 3/14 - Hopefully the club will be open to dining. We've pushed our Hawaii trip 3 times in 2020 already.

We'll miss each other by a week.

Debating whether I want to attempt cycling Haleakala but I'm in pretty crummy shape.

[artemis]

I think future COVID vaccine trials are doomed, unless they are ones combining it with the annual flu shot.

And that is a problem because because we need more than one type of vaccine for this, as not everyone can take the mRNA vaccines. I understand the Novavax vaccine is a protein subunit vaccine + adjuvant, so it should be OK for people who have an allergy to PEG (present in the mRNA vaccines).

[uptoolate]

Might want to be aware of potential interstate travel restrictions. Vaccinated or not, the mood at the top has shifted.

We have had several national and provincial politicians lose cabinet and/or committee positions due to travel to warmer climes over the holiday seasons. And two major healthcare group CEOs have been fired for the same - thankfully they have million dollar severance packages to buffer the trauma. Whew!

[Shant]

And that is a problem because because we need more than one type of vaccine for this, as not everyone can take the mRNA vaccines. I understand the Novavax vaccine is a protein subunit vaccine + adjuvant, so it should be OK for people who have an allergy to PEG (present in the mRNA vaccines).

Is it just the PEG you're thinking of or is there another concern I've overlooked?

[artemis]

Is it just the PEG you're thinking of or is there another concern I've overlooked?

Mostly the PEG (although there may be other ingredients in the lipid coating that trigger severe allergic reactions in some individuals as well). PEG's currently the one we can screen for, though. And while it's not relevant yet because the AstraZeneca vaccine hasn't yet been approved in the US, I wonder if that will be truly safe for individuals who shouldn't be taking a live virus vaccine (even though the virus supposedly can't replicate). Having mRNA, adenovirus-based, and protein subunit vaccines all available gives us the best chance of being able to find a vaccine suitable for every patient. (There's some indications the Novavax vaccine may also be effective as a single-dose vaccine, which would also be a big boon.)

[Shant]

Thanks.

First mover advantage in practise. I always kind of figured Pfizer would have to make all its money now before it gets overtaken by easier to use vaccines but this might give them a bit of a reprieve.

[Tim]

Here in Washington State, Governor Inslee is trying to enlist corporate support and assistance from Starbucks, Microsoft and Costco, among others. Hopefully his goal of 40,000 + vaccinations a day can be achieved.

https://abcnews.go.com/Business/wash...ry?id=75340943

I would expect every company that had political interest in the election to start signaling. Definitely Amazon, FB , Google and Twitter will offer their resources. Oh, Amazon just did. Surprise surprise. Public service announcements getting a shot is likely. Signaling is coming. The question is how can they leverage it. Good corporate citizens.

[pulmdoc]

Does anyone know if biologics like Xolair would negatively impact the efficacy of the Covid vaccine? Would having a biologic in your system affect the response your immune system could build to the vaccine? Thank you.

I use Xolair frequently for my asthma patients. No contraindication to vaccinations.

[Tim]

Kudo's to FLP

https://www.nytimes.com/interactive/2020/us/covid-19-vaccine-doses.html

This seems to provide raw numbers and metrics of the percentages for 1st, 2nd,and used. Found they can be sorted. It does not give the % by priorities because every state is defining them differently. Gives and easy way to slice and dice. The size of the task likely impacts the ramp up in each state. It looks like the high population states are attacking the problem.
FYI

[Jaqen Haghar MD]

I wonder with these new strains of coronavirus that are popping up, if we are now detecting some regular (non-COVID 19 syndrome causing) seasonal coronaviruses. Since we were never surveilling for the normal coronavirus that comes through every year, it seems logical that we might find these now if we are looking carefully.

I imagine it will be difficult initially to sort out which of these causes COVID 19 devastation, and which of these is just a “regular cold” in our current environment with 19 out there.

It will be interesting to see how we tackle this inevitable issue going forward. At some point we may be waging a costly battle with regular, yearly cold viruses growing in the mix. We may have nuclear weapons pointed at the sniffles at some point in the future.